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Title | BBMRI - Large Prospective Cohorts |
Grant Agreement Number | 313010 |
Funding Programmes | FP7 |
Dates | 01/02/2013 - 31/01/2017 |
Project URL | http://bbmri-lpc.iarc.fr/ |
Scientific Domain |
Biological and Medical Sciences |
Type Of Project | CP-CSA-INFRA |
Abstract | In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, and the actual comparability of selected patients. Large prospective cohort (LPC) studies following up initially healthy participants for years or decades are considered more reliable and different diseases can be studied. LPC studies require large numbers of subjects which are costly but particularly benefited from the advent of high throughput techniques providing opportunities for powerful study designs. This project unites the large study sets of the European Biobanking and Biomolecular Research Infrastructure (BBMRI) and the International Agency for Research on Cancer (IARC), thus achieving a worldwide unique scale of integration. Specifically, we aim to:1)Evaluate/improve the harmonization of individual data on health, lifestyle and other exposures;2)Develop/implement harmonized definitions of diseases;3)Improve biobanking and research technologies and develop innovative solutions facilitating high-quality, fair access to samples and data;4)Provide free transnational access by users, through study proposals selected by an open, pan-European call;5)In the framework of these studies, generate and provide access to whole genome sequences, transcriptome, proteome, metabolome and methylome data;6)Build new public-private partnerships involving large-scale prospective cohorts, and strengthening existing ones, allowing transparent industrial access to academic expertise;7) Build a network transferring the expertise of established European large-scale biobanks to new biobank initiatives under development in other countries. |
Coordinator
(Organisation name and Country) |
HELSINGIN YLIOPISTO, Finland |
Partners
(Organisation name and Country) |
KAROLINSKA INSTITUTET, Sweden GENOME RESEARCH LIMITED, United Kingdom NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET, Norway UPPSALA UNIVERSITET, Sweden IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE, United Kingdom FUNDACIO PRIVADA PARC CIENTIFIC DE BARCELONA, Spain TARTU ULIKOOL, Estonia UNIVERSITY OF NEWCASTLE UPON TYNE, United Kingdom CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER, France INTERNATIONAL PREVENTION RESEARCH INSTITUT-IPRI MANAGEMENT, France LEGAL PATHWAYS BV, Netherlands ACADEMISCH ZIEKENHUIS GRONINGEN, Netherlands NASJONALT FOLKEHELSEINSTITUTT, Norway ACADEMISCH ZIEKENHUIS LEIDEN - LEIDS UNIVERSITAIR MEDISCH CENTRUM, Netherlands TERVEYDEN JA HYVINVOINNIN LAITOS, Finland STATENS SERUM INSTITUT, Denmark UNIVERSITEIT MAASTRICHT, Netherlands MEDIZINISCHE UNIVERSITAT GRAZ, Austria ISLENSK ERFDAGREINING EHF, Iceland KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN, Germany CAMBRIDGE PROTEIN ARRAYS LTD, United Kingdom PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS, Hungary The Research Institute of the Mc Gill University Health Centre, Canada LATVIJAS BIOMEDICINAS PETIJUMU UN STUDIJU CENTRS, Latvia SVEUCILISTE U SPLITU (UNIVERSITY OF SPLIT), Croatia (Hrvatska) Wroclawskie Centrum Badan EIT+ Sp z o.o, Poland MedLawconsult (Van Veen, Toegepast Gezondheidsrecht), Netherlands |