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Project

INFRAFRONTIER

Title Infrafrontier The European infrastructure for phenotyping and archiving of model mammalian genomes
Grant Agreement Number 211404
Funding Programmes FP7
Dates 01/03/2008 - 29/02/2012
Project URL http://www.infrafrontier.eu
Scientific Domain Biological and Medical Sciences
Action Line Preparatory phase
Type Of Project CP-CSA-INFRA
Abstract Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper characterization (Mouse Clinics), archiving and dissemination of mouse disease models to the research laboratories. The current capacities, governance structures and funding strategies of existing infrastructures will not be able to serve the upcoming urgent needs. Thus it is imperative to organise and establish now an efficient distributed infrastructure for the phenotyping, archiving and dissemination of mouse models on a well concerted, large-scale and pan-European level. This will be a prerequisite for maintaining Europe s leading role in the functional annotation of the mouse genome. Infrafrontier will guarantee the accessibility of mouse models and will be essential to facilitate their exploitation. Infrafrontier integrates 15 European laboratories with exceptional track records to implement and run large-scale infrastructures.
Partners
(Organisation name and Country)
KOBENHAVNS UNIVERSITET, Denmark
KAROLINSKA INSTITUTET, Sweden
OULUN YLIOPISTO, Finland
GENOME RESEARCH LIMITED, United Kingdom
MEDICAL RESEARCH COUNCIL, United Kingdom
HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH, Germany
The Swedish Research Council - Vetenskapsrȯdet, Sweden
GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS (General Secretariat for Research & Technology), Greece
Ministry of Education Youth and Sports, Czech Republic
German Federal Ministry of Education and Research, Germany
BIOCEV z.s.p.o., Czech Republic
USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYSKUMNA INSTITUCE, Czech Republic
MINISTERO DELLA SALUTE, Italy
Toronto Centre for Phenogenomics Inc., Canada
VETERINAERMEDIZINISCHE UNIVERSITAET WIEN, Austria
FUNDACION PARA EL CONOCIMIENTO MADRIMASD, Spain
FUNDACION PARQUE CIENTIFICO DE MADRID, Spain
DEPARTAMENT DE SALUT - GENERALITAT DE CATALUNYA, Spain
HERMANN VON HELMHOLTZ-GEMEINSCHAFT DEUTSCHER FORSCHUNGSZENTREN EV, Germany
UNIVERSITAT AUTONOMA DE BARCELONA, Spain
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING, Greece
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, Spain
CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE, France
FUNDACAO CALOUSTE GULBENKIAN, Portugal