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Title | Infrafrontier The European infrastructure for phenotyping and archiving of model mammalian genomes |
Grant Agreement Number | 211404 |
Funding Programmes | FP7 |
Dates | 01/03/2008 - 29/02/2012 |
Project URL | http://www.infrafrontier.eu |
Scientific Domain |
Biological and Medical Sciences |
Action Line | Preparatory phase |
Type Of Project | CP-CSA-INFRA |
Abstract | Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper characterization (Mouse Clinics), archiving and dissemination of mouse disease models to the research laboratories. The current capacities, governance structures and funding strategies of existing infrastructures will not be able to serve the upcoming urgent needs. Thus it is imperative to organise and establish now an efficient distributed infrastructure for the phenotyping, archiving and dissemination of mouse models on a well concerted, large-scale and pan-European level. This will be a prerequisite for maintaining Europe s leading role in the functional annotation of the mouse genome. Infrafrontier will guarantee the accessibility of mouse models and will be essential to facilitate their exploitation. Infrafrontier integrates 15 European laboratories with exceptional track records to implement and run large-scale infrastructures. |
Partners
(Organisation name and Country) |
KOBENHAVNS UNIVERSITET, Denmark KAROLINSKA INSTITUTET, Sweden OULUN YLIOPISTO, Finland GENOME RESEARCH LIMITED, United Kingdom MEDICAL RESEARCH COUNCIL, United Kingdom HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH, Germany The Swedish Research Council - Vetenskapsrȯdet, Sweden GENIKI GRAMMATIA EREVNAS KAI TECHNOLOGIAS (General Secretariat for Research & Technology), Greece Ministry of Education Youth and Sports, Czech Republic German Federal Ministry of Education and Research, Germany BIOCEV z.s.p.o., Czech Republic USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYSKUMNA INSTITUCE, Czech Republic MINISTERO DELLA SALUTE, Italy Toronto Centre for Phenogenomics Inc., Canada VETERINAERMEDIZINISCHE UNIVERSITAET WIEN, Austria FUNDACION PARA EL CONOCIMIENTO MADRIMASD, Spain FUNDACION PARQUE CIENTIFICO DE MADRID, Spain DEPARTAMENT DE SALUT - GENERALITAT DE CATALUNYA, Spain HERMANN VON HELMHOLTZ-GEMEINSCHAFT DEUTSCHER FORSCHUNGSZENTREN EV, Germany UNIVERSITAT AUTONOMA DE BARCELONA, Spain BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING, Greece CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, Spain CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE, France FUNDACAO CALOUSTE GULBENKIAN, Portugal |